SCHEMBL28613151

SCHEMBL28613151

[CH2]C(CCC/C=C\CCCCC)CCC/C=C\CCCCCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.52
TRPV1 Q8NER1 1/20 0.52
TSHR P16473 1/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
CYP3A4 P08684 2/20 0.46
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26121098 0.98 FAAH (0.48) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL23795035 0.98 FAAH (0.48) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL29044611 0.98 FAAH (0.48) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL16569100 0.95 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL10979364 0.95 FAAH (0.52) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL29044596 0.93 FAAH (0.45) FAAHTRPV1KMT2AMEN1CYP3A4
SCHEMBL11223487 0.91 FAAH (0.48) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL6949367 0.84 FAAH (0.50) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL6949363 0.84 FAAH (0.50) FAAHTRPV1TSHRKMT2AMEN1
SCHEMBL11671965 0.82 TAS1R3 (0.33) FAAHTRPV1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113286622-A Silicon-containing cationic lipids 阿布特斯生物制药公司 2021-08-20 CN claimed
CN-115768438-A Lipid nanoparticles for delivery of therapeutic agents to the lung 盖纳万科学有限公司 2023-03-07 CN disclosed
CN-113286622-A Silicon-containing cationic lipids 阿布特斯生物制药公司 2021-08-20 CN disclosed