Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | APAF1 | O14727 | 2/20 | 0.40 |
| ▸ | TDP2 | O95551 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | GALK1 | P51570 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28535153 | 0.84 | CA1 (0.41) | KDM4EMAPTALDH1A1POLBLMNA | |
| SCHEMBL28535248 | 0.84 | CA1 (0.41) | KDM4EMAPTALDH1A1POLBLMNA | |
| SCHEMBL28541543 | 0.83 | CA1 (0.47) | KDM4EMAPTALDH1A1POLBLMNA | |
| SCHEMBL28533193 | 0.79 | MAPT (0.39) | KDM4EMAPTALDH1A1POLBLMNA | |
| SCHEMBL28534752 | 0.79 | MAPT (0.39) | KDM4EMAPTALDH1A1POLBLMNA | |
| SCHEMBL12083380 | 0.76 | ALDH1A1 (0.45) | KDM4EAPAF1TDP2NSD2MAPT | |
| SCHEMBL29940790 | 0.76 | ALDH1A1 (0.45) | KDM4EAPAF1TDP2NSD2MAPT | |
| SCHEMBL28055380 | 0.76 | ALDH1A1 (0.45) | KDM4EAPAF1TDP2NSD2MAPT | |
| SCHEMBL1875543 | 0.72 | SMN1; SMN2 (0.42) | ABL1ALDH1A1LMNASLC6A3KMT2A | |
| SCHEMBL1874449 | 0.72 | SMN1; SMN2 (0.42) | ABL1ALDH1A1LMNASLC6A3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108911980-B | Method for kinetic resolution of alpha-hydroxy-beta-dicarbonyl compound enantiomer under micro-reaction condition or conventional reaction condition | 吉林大学 | 2021-06-29 | — | — | CN | disclosed |