SCHEMBL29940790

SCHEMBL29940790

COC(=O)C1(O)Cc2ccccc2C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
POLB P06746 4/20 0.45
HTT P42858 4/20 0.45
LMNA P02545 3/20 0.45
KDM4E B2RXH2 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 2/20 0.45
GAA P10253 1/20 0.45
L3MBTL1 Q9Y468 4/20 0.43
NPSR1 Q6W5P4 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 3/20 0.38
TP53 P04637 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALOX12 P18054 2/20 0.37
RECQL P46063 2/20 0.37
TSHR P16473 2/20 0.37
MAPK1 P28482 2/20 0.37
CA1 P00915 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28055380 1.00 ALDH1A1 (0.45) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL12083380 1.00 ALDH1A1 (0.45) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL12083397 0.84 HTR2A (0.47) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL12083374 0.82 MCOLN3 (0.42) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL12083294 0.81 L3MBTL1 (0.44) ALDH1A1POLBHTTLMNAL3MBTL1
SCHEMBL1786991 0.81 SMN1; SMN2 (0.51) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL29597476 0.81 SMN1; SMN2 (0.51) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL28118429 0.81 ALDH1A1 (0.49) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL29476746 0.81 HTT (0.45) ALDH1A1POLBHTTLMNAKDM4E
SCHEMBL8871607 0.81 ALDH1A1 (0.49) ALDH1A1POLBHTTLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111579658-B Content analysis method of indoxacarb chiral intermediate 京博农化科技有限公司 2022-09-27 CN claimed
CN-114082446-B Chiral zirconium catalyst for preparing chiral alpha-hydroxy-beta-keto ester compound and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2023-12-22 CN disclosed
CN-113277948-B Preparation method for preparing high-content indoxacarb intermediate 京博农化科技有限公司 2022-09-27 CN disclosed