Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613127 | 0.85 | TRPV1 (0.49) | TRPV1NPC1RAB9AEPHX1GAA | |
| SCHEMBL28608026 | 0.81 | FAAH (0.55) | KMT2AMEN1GAAALDH1A1MAPT | |
| SCHEMBL28613585 | 0.80 | HDAC1 (0.49) | TRPV1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL28920263 | 0.79 | FAAH (0.50) | TRPV1KMT2AMEN1RAB9AGAA | |
| SCHEMBL28674177 | 0.77 | FAAH (0.48) | TRPV1KMT2AMEN1RAB9AEPHX1 | |
| SCHEMBL28693808 | 0.75 | FAAH (0.45) | KMT2AMEN1RAB9AEPHX1EPHX2 | |
| SCHEMBL29331891 | 0.74 | EPHX1 (0.61) | TRPV1KMT2AUSP2MEN1NPC1 | |
| SCHEMBL10521499 | 0.71 | EPHX1 (0.58) | TRPV1KMT2AUSP2MEN1NPC1 | |
| SCHEMBL28674191 | 0.71 | MEN1 (0.44) | KMT2AMEN1RAB9AEPHX1EPHX2 | |
| SCHEMBL13664692 | 0.71 | EPHX1 (0.53) | TRPV1KMT2AUSP2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113233996-B | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2022-05-20 | — | — | CN | claimed |
| CN-113233996-A | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2021-08-10 | — | — | CN | claimed |
| CN-113233996-B | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113233996-A | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2021-08-10 | — | — | CN | disclosed |