Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28674177 | 0.98 | FAAH (0.48) | FAAHLMNANPSR1GAARAB9A | |
| SCHEMBL28693808 | 0.95 | FAAH (0.45) | FAAHLMNANPSR1GAARAB9A | |
| SCHEMBL28674191 | 0.92 | MEN1 (0.44) | FAAHLMNANPSR1GAARAB9A | |
| SCHEMBL28613127 | 0.85 | TRPV1 (0.49) | LMNANPSR1GAARAB9ASMN1; SMN2 | |
| SCHEMBL28613585 | 0.85 | HDAC1 (0.49) | FAAHRAB9ASMN1; SMN2HDAC1TRPV1 | |
| SCHEMBL2112321 | 0.81 | FAAH (0.52) | FAAHLMNANPSR1GAASMN1; SMN2 | |
| SCHEMBL28613261 | 0.79 | TRPV1 (0.52) | FAAHLMNANPSR1GAARAB9A | |
| SCHEMBL28608026 | 0.78 | FAAH (0.55) | FAAHLMNANPSR1GAASMN1; SMN2 | |
| SCHEMBL5510278 | 0.78 | NPSR1 (0.50) | FAAHLMNANPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL26110622 | 0.76 | ALDH1A1 (0.41) | LMNAKMT2AHPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896712-B | Diamide compound containing cyclic amino acid | 华东理工大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-113233996-B | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2022-05-20 | — | — | CN | disclosed |
| CN-113896712-A | Diamide compound containing cyclic amino acid | 华东理工大学 | 2022-01-07 | — | — | CN | disclosed |
| CN-113233996-A | Novel TRPV1 antagonistic/FAAH inhibition double-target drug, and preparation method and application thereof | 河南大学 | 2021-08-10 | — | — | CN | disclosed |