Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL29039967 | 0.93 | TSHR (0.32) | ALDH1A1TSHR | |
| SCHEMBL75111 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHR | |
| Tert-Butyl Hydroperoxide SCHEMBL7633137 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHR | |
| Bicarbonate SCHEMBL26105671 | 0.76 | TSHR (0.41) | ALDH1A1POLBHMGCRCHRM1TBXA2R | |
| SCHEMBL8983691 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TSHR | |
| SCHEMBL27364953 | 0.76 | POLB (0.32) | ALDH1A1POLBGAAHMGCRCHRM1 | |
| Bicarbonate SCHEMBL16738136 | 0.76 | TSHR (0.42) | ALDH1A1GAAHMGCRCHRM1TBXA2R | |
| SCHEMBL7360362 | 0.74 | GAA (0.31) | GAA | |
| Water SCHEMBL28429694 | 0.74 | POLB (0.31) | ALDH1A1POLBGAAHMGCRCHRM1 | |
| Tert-Butyl Hydroperoxide SCHEMBL25265357 | 0.72 | ALDH1A1 (0.45) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105717747-B | Photosensitive resin composition and application thereof | 奇美实业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-105717743-B | Photosensitive resin composition and application thereof | 奇美实业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113302734-A | Curable composition and cured product | 可舒磨润滑油株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-110663085-B | Solid electrolyte composition, solid electrolyte-containing sheet, all-solid-state secondary battery, and method for producing solid electrolyte-containing sheet and all-solid-state secondary battery | 富士胶片株式会社 | 2021-04-20 | — | — | CN | disclosed |
| CN-111848846-A | Preparation method and application of vinyl chloride polymer | 安徽华塑股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-110663085-A | Solid electrolyte composition, solid electrolyte-containing sheet, all-solid-state secondary battery, and method for producing solid electrolyte-containing sheet and all-solid-state secondary battery | 富士胶片株式会社 | 2020-01-07 | — | — | CN | disclosed |