Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PREP | P48147 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308992 | 0.90 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL24420805 | 0.89 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL20231316 | 0.86 | CA12 (0.41) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL29614665 | 0.86 | CA12 (0.41) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL7257494 | 0.84 | HPSE (0.47) | CA12CA1CA9HPSE | |
| SCHEMBL4753702 | 0.81 | CA12 (0.46) | CA12CA1CA9ALDH1A1PREP | |
| SCHEMBL14786374 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4ELTB4RLTB4R2AKR1C3 | |
| SCHEMBL29061089 | 0.80 | USP14 (0.35) | ALDH1A1DRD2HPGD | |
| SCHEMBL2317055 | 0.79 | AKR1C3 (0.50) | ALDH1A1KDM4EAKR1C3AKR1C2HPGD | |
| SCHEMBL1604135 | 0.78 | CA12 (0.43) | CA12CA1CA9ALDH1A1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745295-A | BRM targeting compounds and related methods of use | 普莱鲁德疗法有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113164775-A | Polycyclic compounds and methods for rapid accelerated targeted degradation of fibrosarcoma polypeptides | 阿尔维纳斯运营股份有限公司 | 2021-07-23 | — | — | CN | disclosed |