Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6196145 | 0.91 | KDM4E (0.41) | ALDH1A1L3MBTL1KDM4EHPGDMEN1 | |
| SCHEMBL6238419 | 0.80 | JAK2 (0.33) | ALDH1A1KDM4EHPGDTDP1SMN1; SMN2 | |
| SCHEMBL482463 | 0.79 | HPGD (0.39) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL9444798 | 0.79 | MEN1 (0.33) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL3653566 | 0.77 | KCNA3 (0.33) | — | |
| SCHEMBL8583545 | 0.77 | — | — | |
| SCHEMBL219417 | 0.77 | KDM4E (0.56) | ALDH1A1L3MBTL1KDM4EHPGDTDP1 | |
| SCHEMBL216551 | 0.77 | ADRB2 (0.51) | ALDH1A1KDM4EUSP2TDP1MEN1 | |
| SCHEMBL3124829 | 0.76 | — | — | |
| SCHEMBL4354869 | 0.76 | KCNA3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195502-A | Macrocyclic influenza endonuclease inhibitors | 詹森生物制药有限公司 | 2021-07-30 | — | — | CN | disclosed |