Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | STAT6 | P42226 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613870 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL30399930 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL12420180 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL31561667 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL9304930 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL9304918 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL5872635 | 0.78 | KMT2A (0.51) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL5872634 | 0.78 | KMT2A (0.51) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL11174003 | 0.75 | KMT2A (0.49) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL28612621 | 0.75 | GAA (0.56) | KMT2AHPGDMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292500-B | Difluoromethyl building block and one-pot derivatization reaction thereof | 台州学院 | 2023-05-09 | — | — | CN | disclosed |
| CN-113292500-A | Difluoromethyl building block and one-pot derivatization reaction thereof | 台州学院 | 2021-08-24 | — | — | CN | disclosed |