Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304918 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL12420180 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL31561667 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL5872634 | 0.80 | KMT2A (0.51) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL5872635 | 0.80 | KMT2A (0.51) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL30399930 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL28613871 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL28613870 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL11174003 | 0.78 | KMT2A (0.49) | SMN1; SMN2LMNASTAT6KMT2AASAH1 | |
| SCHEMBL28918168 | 0.76 | LMNA (0.44) | SMN1; SMN2LMNASTAT6KMT2AASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374701-A | Crosslinkable polymers of high strength free of structural defects | HAY ALLAN S (CA) | 1994-12-20 | — | — | US | disclosed |
| US-5233046-A | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALLAN S (CA) | 1993-08-03 | — | — | US | disclosed |
| WO-1993009079-A1 | DIARYLACETYLENES, ENAMINES AND ACETYLENIC POLYMERS AND THEIR PRODUCTION | HAY ALAN S (CA) | 1993-05-13 | — | — | WO | disclosed |