Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GPR3 | P46089 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1268537 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL30804387 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL6343134 | 0.82 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| Urea SCHEMBL28581689 | 0.78 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL29096075 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL30880427 | 0.74 | KDM4E (0.50) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL9715631 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL30623756 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL476707 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1SMN1; SMN2PARP1MEN1 | |
| SCHEMBL17942038 | 0.73 | KDM4E (0.69) | KDM4EALDH1A1PARP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735401-B | Substituted dihydropyrrolopyrazole derivatives | 宇部兴产株式会社 | 2021-08-31 | — | — | CN | disclosed |