Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PARP1 | P09874 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GPR3 | P46089 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29096075 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL30804387 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL1268537 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL5528637 | 0.82 | KDM4E (0.59) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL31175987 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL28784055 | 0.77 | DAO (0.62) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL17942038 | 0.77 | KDM4E (0.69) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL27804429 | 0.76 | PADI4 (0.48) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL26693286 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1PARP1LMNAMEN1 | |
| SCHEMBL741833 | 0.74 | POLB (0.53) | KDM4EALDH1A1PARP1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8604020-B2 | Fluoroquinolone carboxylic acid molecular crystals | BAUSCH & LOMB INCORPORATED (US) | 2013-12-10 | — | — | US | disclosed |
| US-20130252946-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | BAUSCH & LOMB INCORPORATED (US) | 2013-09-26 | — | — | US | disclosed |
| US-8481526-B2 | Fluoroquinolone carboxylic acid molecular crystals | BAUSCH & LOMB INCORPORATED (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2411369-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | Bausch & Lomb Incorporated (US) | 2012-02-01 | — | — | EP | disclosed |
| US-20100311731-A1 | Fluoroquinolone Carboxylic Acid Molecular Crystals | SALIX PHARMACEUTICALS, INC. | 2010-12-09 | — | — | US | disclosed |
| WO-2010111116-A1 | FLUOROQUINOLONE CARBOXYLIC ACID MOLECULAR CRYSTALS | BAUSCH & LOMB INCORPORATED (US) | 2010-09-30 | — | — | WO | disclosed |