SCHEMBL28614786

SCHEMBL28614786

CC(C)(C)c1ccc2c(c1)-c1c(cccc1C(C)(C)C)[CH]2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
NPC1 O15118 1/20 0.39
PLA2G1B P04054 1/20 0.39
NFKB1 P19838 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ATG4B Q9Y4P1 1/20 0.39
CA2 P00918 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4468064 0.87 ALDH1A1 (0.39) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL2045383 0.80 CA2 (0.40) ALDH1A1CA2TDP1TSHRKIF11
SCHEMBL344810 0.78 ALDH1A1 (0.47) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL2050307 0.78 CA2 (0.48) ALDH1A1CA2TDP1TSHRKIF11
SCHEMBL2051686 0.77 ALDH1A1 (0.53) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL215708 0.77 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27845457 0.76 ALDH1A1 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL27486458 0.76 ALDH1A1 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL26071407 0.76 ALDH1A1 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL28502707 0.76 ALDH1A1 (0.45) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113302213-A Catalyst for olefin polymerization and process for producing olefin polymer containing polar group 国立大学法人东京大学 2021-08-24 CN disclosed