Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603992 | 1.00 | KDR (0.39) | KDRMAOAMAOBMAPTNPC1 | |
| SCHEMBL28919461 | 0.95 | MAOA (0.42) | MAOAMAOBMAPTNPC1RAB9A | |
| Aza-Flavanone SCHEMBL28606333 | 0.93 | MAOA (0.45) | MAOAMAOBMAPTHCRTR1HCRTR2 | |
| Aza-Flavanone SCHEMBL28608106 | 0.93 | KDR (0.42) | KDRMAPTNPC1RAB9AMEN1 | |
| SCHEMBL28603909 | 0.90 | KDR (0.40) | KDRMAOAMAOBMAPTNPC1 | |
| SCHEMBL28614837 | 0.90 | KDR (0.40) | KDRMAOAMAOBMAPTNPC1 | |
| SCHEMBL28919462 | 0.89 | FPR1 (0.48) | RAB9AMEN1KMT2ATNKS2FPR1 | |
| SCHEMBL28601602 | 0.89 | FPR1 (0.48) | RAB9AMEN1KMT2ATNKS2FPR1 | |
| SCHEMBL28604164 | 0.89 | GAA (0.42) | KDRMAPTNPC1RAB9AMEN1 | |
| SCHEMBL28612430 | 0.89 | MAOA (0.40) | MAOAMAOBNPC1RAB9AHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558756-B | 2-aryl-2, 3-dihydro-4 (1H) -quinolinone semicarbazone compound and application thereof | 沈阳药科大学 | 2021-08-03 | — | — | CN | claimed |