Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | ATG4B | Q9Y4P1 | 12/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 11/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1206901 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL1206905 | 1.00 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11763070 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL846032 | 0.95 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL846033 | 0.95 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6287182 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11766313 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL489898 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL6279559 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11765995 | 0.93 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329998-A | Sulfonimidyl amide compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-31 | — | — | CN | disclosed |