Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18591561 | 1.00 | MAPT (0.41) | MAPTMEN1KMT2ANPSR1TP53 | |
| SCHEMBL18579331 | 0.88 | PTGS2 (0.43) | MAPTMEN1KMT2AHTTNPC1 | |
| SCHEMBL18579333 | 0.88 | PTGS2 (0.43) | MAPTMEN1KMT2AHTTNPC1 | |
| SCHEMBL18579349 | 0.83 | PTGS2 (0.37) | MAPTMEN1KMT2ANPSR1TP53 | |
| SCHEMBL18579351 | 0.83 | PTGS2 (0.37) | MAPTMEN1KMT2ANPSR1TP53 | |
| SCHEMBL18579381 | 0.83 | EPHX2 (0.43) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL18579382 | 0.83 | EPHX2 (0.43) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL18591544 | 0.82 | CA12 (0.40) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL28618859 | 0.82 | CA12 (0.40) | MAPTMEN1KMT2ALMNANPC1 | |
| SCHEMBL28629677 | 0.79 | CYP2D6 (0.36) | KMT2ATP53SMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025189-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-02 | — | — | CN | disclosed |