Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624282 | 0.89 | HDAC1 (0.34) | GRIK1GRIK2HDAC1CCNA2CDK2 | |
| SCHEMBL28624281 | 0.89 | HDAC1 (0.34) | GRIK1GRIK2HDAC1CCNA2CDK2 | |
| SCHEMBL28628307 | 0.86 | LMNA (0.38) | CYP2D6GRIK1GRIK2HDAC1HDAC8 | |
| SCHEMBL28628308 | 0.86 | LMNA (0.38) | CYP2D6GRIK1GRIK2HDAC1HDAC8 | |
| SCHEMBL28615670 | 0.86 | PPARD (0.36) | SMN1; SMN2RXRAGRIN1GRIN2B | |
| SCHEMBL28615666 | 0.86 | PPARD (0.36) | SMN1; SMN2RXRAGRIN1GRIN2B | |
| SCHEMBL18579738 | 0.85 | KDM4E (0.36) | CYP2D6GRIK1GRIK2HDAC1HDAC8 | |
| SCHEMBL18579736 | 0.85 | KDM4E (0.36) | CYP2D6GRIK1GRIK2HDAC1HDAC8 | |
| SCHEMBL28624292 | 0.84 | PDE10A (0.36) | CCNA2CDK2CCNA1KDM4E | |
| SCHEMBL28624296 | 0.84 | PDE10A (0.36) | CCNA2CDK2CCNA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108025189-B | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 美国陶氏益农公司 | 2021-07-02 | — | — | CN | disclosed |