Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864213 | 1.00 | GAA (0.34) | GAACRBNDDB1TSHRMAPK1 | |
| SCHEMBL4773108 | 0.84 | DDB1 (0.46) | CRBNDDB1 | |
| SCHEMBL1773976 | 0.77 | CRBN (0.40) | GAACRBNDDB1MAPK1MAP3K14 | |
| SCHEMBL756451 | 0.76 | CRBN (0.38) | GAACRBNDDB1TSHRMAP3K14 | |
| SCHEMBL8576306 | 0.76 | EPHX2 (0.42) | GAA | |
| SCHEMBL10633587 | 0.76 | EPHX2 (0.42) | GAA | |
| SCHEMBL57232 | 0.75 | MAP3K14 (0.39) | GAACRBNDDB1TSHRMAP3K14 | |
| SCHEMBL28585016 | 0.75 | LMNA (0.31) | GAA | |
| SCHEMBL3836555 | 0.75 | EPHX2 (0.40) | GAACRBNDDB1TSHR | |
| SCHEMBL27675961 | 0.75 | IDO1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112512589-A | Dimeric immunomodulatory compounds against CEREBLON-based mechanisms | H·李·莫菲特癌症中心研究有限公司 | 2021-03-16 | — | — | CN | disclosed |
| CN-109153644-A | SMALL MOLECULES AGAINST CEREBLON TO ENHANCE EFFECTOR T CELL FUNCTION | H·李·莫菲特癌症中心研究有限公司 | 2019-01-04 | — | — | CN | disclosed |