SCHEMBL57232

SCHEMBL57232

CC(=O)OC1CC(=O)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.39
POLB P06746 1/20 0.38
CRBN Q96SW2 6/20 0.38
DDB1 Q16531 5/20 0.38
TSHR P16473 2/20 0.33
MEN1 O00255 1/20 0.33
APEX1 P27695 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.33
GAA P10253 1/20 0.33
CYP19A1 P11511 1/20 0.32
NPC1 O15118 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28226112 0.83 DDB1 (0.33) POLBCRBNDDB1CYP19A1
SCHEMBL8080480 0.82 POLB (0.33) POLBTSHRALOX15
SCHEMBL10597719 0.82 MAP3K14 (0.38) MAP3K14CRBNDDB1TSHRGAA
SCHEMBL2128127 0.82 CRBN (0.35) MAP3K14POLBCRBNDDB1MEN1
SCHEMBL4396268 0.82 CRBN (0.35) MAP3K14CRBNDDB1MEN1APEX1
SCHEMBL3949247 0.82 MAP3K14 (0.40) MAP3K14CRBNDDB1TSHRMEN1
SCHEMBL7264550 0.82 MAP3K14 (0.40) MAP3K14CRBNDDB1TSHRMEN1
SCHEMBL756451 0.81 CRBN (0.38) MAP3K14CRBNDDB1TSHRMEN1
SCHEMBL8092079 0.81 POLB (0.32) POLBTSHRALOX15
SCHEMBL26328452 0.81 DDB1 (0.52) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114438048-B Urate oxidase preparation and application thereof 重庆派金生物科技有限公司 2024-10-22 CN claimed
CN-118497161-A Polyethylene glycol modified urate oxidase 重庆派金生物科技有限公司 2024-08-16 CN claimed
CN-117866929-A Pegylated arginine deiminase dimer preparation and use thereof 重庆派金生物科技有限公司 2024-04-12 CN claimed
WO-2023079959-A1 SILICONE ADDITIVE FOR RESIN MODIFICATION AND CURABLE RESIN COMPOSITION CONTAINING SAME 信越化学工業株式会社 2023-05-11 WO claimed
CN-115997016-A Composition comprising nucleic acid nanoparticles having modular functional groups 西克斯福德生物科学有限公司 2023-04-21 CN claimed
CN-114438048-A Urate oxidase preparation and application thereof 重庆派金生物科技有限公司 2022-05-06 CN claimed
CN-111909906-A Urate oxidase modified by polyethylene glycol 重庆派金生物科技有限公司 2020-11-10 CN claimed
WO-2006006924-A1 METHOD AND KIT FOR PEPTIDE ANALYSIS GE HEALTHCARE BIO-SCIENCES AB (SE) 2006-01-19 WO claimed
EP-1432992-A2 CONTROLLING ISOTOPE EFFECTS DURING FRACTIONATION OF ANALYTES PURDUE RESEARCH FOUNDATION (US) 2004-06-30 EP claimed
EP-1370295-A2 NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY GENCELL S.A. (FR) 2003-12-17 EP claimed
WO-2003027682-A2 CONTROLLING ISOTOPE EFFECTS DURING FRACTIONATION OF ANALYTES PURDUE RESEARCH FOUNDATION (US) 2003-04-03 WO claimed
WO-2002043769-A2 NEUTRAL AND ANIONIC COLLOIDAL PARTICLES FOR GENE DELIVERY GENCELL S.A. (FR) 2002-06-06 WO claimed
CN-120202229-A Curable polymer compound and resin composition containing the same 日本化药株式会社 2025-06-24 CN disclosed
CN-118852124-A Preparation method and application of indole alkaloid compound 广东医科大学 2024-10-29 CN disclosed
CN-114438048-B Urate oxidase preparation and application thereof 重庆派金生物科技有限公司 2024-10-22 CN disclosed
CN-115768805-B Polymer compound and resin composition containing the same 日本化药株式会社 2024-10-01 CN disclosed
US-4801579-A NUTRIENT SOLUTIONS, WATER SOLUBILITY BLEIBERGER BERGWERKS UNION (AT) 1989-01-31 US disclosed
US-4783442-A B-cell differentiating peptides ORTHO PHARMACEUTICAL CORPORATION (US) 1988-11-08 US disclosed
EP-0203621-A1 C-20-modified macrolide derivatives ELI LILLY AND COMPANY (US) 1986-12-03 EP disclosed
EP-0104028-A1 C-20-modified macrolide derivatives ELI LILLY AND COMPANY (US) 1984-03-28 EP disclosed