Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226609 | 0.82 | GRIN2D (0.48) | EPHX2LMNAALDH1A1CA12CA2 | |
| SCHEMBL26027255 | 0.78 | LMNA (0.36) | EPHX2LMNAALDH1A1CA12CA2 | |
| SCHEMBL13968179 | 0.77 | EPHX2 (0.61) | EPHX2CA12CA2CA7CA1 | |
| SCHEMBL14820082 | 0.73 | EPHX2 (0.56) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14805820 | 0.73 | EPHX2 (0.56) | EPHX2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1160901 | 0.73 | LMNA (0.42) | EPHX2LMNAALDH1A1CA12CA2 | |
| SCHEMBL75195 | 0.71 | EPHX2 (0.74) | EPHX2EPHX1GAA | |
| SCHEMBL13195555 | 0.71 | LMNA (0.36) | EPHX2LMNAALDH1A1CA12CA2 | |
| SCHEMBL1160739 | 0.71 | LMNA (0.36) | EPHX2LMNAALDH1A1CA12CA2 | |
| SCHEMBL1406851 | 0.71 | LMNA (0.36) | EPHX2LMNAALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107556244-B | Fused ring compound, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2021-09-03 | — | — | CN | disclosed |