SCHEMBL2861528

SCHEMBL2861528

Cc1cc([C@@]2(c3cc(C)c(OP(=O)(O)O)cc3C(C)C)OC(=O)c3ccccc32)c(C(C)C)cc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.57
LMNA P02545 6/20 0.57
NPSR1 Q6W5P4 3/20 0.57
CYP3A4 P08684 3/20 0.57
CYP2C19 P33261 2/20 0.57
TP53 P04637 2/20 0.57
ALOX15 P16050 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C9 P11712 1/20 0.57
PAX8 Q06710 1/20 0.57
HIF1A Q16665 1/20 0.57
POLB P06746 2/20 0.48
GPR55 Q9Y2T6 2/20 0.48
ALOX12 P18054 1/20 0.48
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
TDP1 Q9NUW8 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL592057 1.00 MAPT (0.57) MAPTLMNANPSR1CYP3A4CYP2C19
Phosphoric Acid SCHEMBL11191627 0.88 MAPT (0.65) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL62717 0.87 MAPT (0.73) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL8377651 0.86 MAPT (0.71) MAPTLMNANPSR1CYP3A4CYP2C19
Phosphoric Acid SCHEMBL10946095 0.85 MAPT (0.64) MAPTLMNANPSR1CYP3A4CYP2C19
Alcohol SCHEMBL10800077 0.83 MAPT (0.67) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL592056 0.82 MAPT (0.76) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL7555225 0.78 MAPT (0.50) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL6676502 0.77 LMNA (0.74) MAPTLMNANPSR1CYP3A4CYP2C19
SCHEMBL5350184 0.77 LMNA (0.60) MAPTLMNANPSR1CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220381698-A1 Methods and Reagents Useful for Verification of the Integrity of a Urine Sample and the Detection of Counterfeit Urine Vision Diagnostics, Inc. 2022-12-01 US disclosed
US-11493498-B2 Assays and methods for diagnosing substance use disorder Vision Diagnostics, Inc. (US) 2022-11-08 US disclosed
US-11493497-B1 Assays and methods for diagnosing substance use disorder Vision Diagnostics, Inc. (US) 2022-11-08 US disclosed
US-11460409-B1 Methods and reagents useful for verification of the integrity of a urine sample and the detection of counterfeit urine Vision Diagnostics, Inc. (US) 2022-10-04 US disclosed
US-20220128540-A1 ASSAYS AND METHODS FOR DIAGNOSING SUBSTANCE USE DISORDER Vision Diagnostics, Inc. 2022-04-28 US disclosed
US-10589003-B2 Methods for coating surfaces with antimicrobial agents THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-03-17 US disclosed
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-10-25 US disclosed
US-7713472-B2 Antiseptic derivatives with broad spectrum antimicrobial activity for the impregnation of surfaces BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-05-11 US disclosed
US-7651661-B2 Medical devices with broad spectrum antimicrobial activity BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-01-26 US disclosed
US-20080183152-A1 MEDICAL DEVICES WITH BROAD SPECTRUM ANTIMICROBIAL ACTIVITY RAAD ISSAM 2008-07-31 US disclosed
US-20070154621-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2007-07-05 US disclosed
US-20050197634-A1 Methods for coating and impregnating medical devices with antiseptic compositions BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-09-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10589003-B2 Methods for coating surfaces with antimicrobial agents CUTA, CD63, CDC37 MAPT 3347/4885LMNA 3795/4885NPSR1 3513/4885
US-20180303977-A1 METHODS FOR COATING SURFACES WITH ANTIMICROBIAL AGENTS CUTA, CD63, CDC37 MAPT 3347/4885LMNA 3795/4885NPSR1 3513/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.