Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900671 | 0.89 | KMT2A (0.78) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL28576782 | 0.78 | RAB9A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL2682787 | 0.78 | KMT2A (1.00) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL558024 | 0.78 | KMT2A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL6153838 | 0.78 | KMT2A (1.00) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL118567 | 0.78 | KMT2A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL1673852 | 0.78 | KMT2A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL1260494 | 0.78 | KMT2A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL6468984 | 0.78 | RAB9A (0.64) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL95791 | 0.78 | KMT2A (0.58) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307781-B | Synthesis method of 1,2, 3-thiadiazole derivative | 新疆大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-114573485-B | Method for synthesizing alkynyl alkyl sulfide | 华南理工大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-114573485-A | Method for synthesizing alkynyl alkyl thioether | 华南理工大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-113307781-A | Synthetic method of 1,2,3-thiadiazole derivative | 新疆大学 | 2021-08-27 | — | — | CN | disclosed |