Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | CDC25C | P30307 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900671 | 0.89 | KMT2A (0.78) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1260494 | 0.78 | KMT2A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28615396 | 0.78 | KMT2A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL28576782 | 0.78 | RAB9A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1673852 | 0.78 | KMT2A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL6153838 | 0.78 | KMT2A (1.00) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL118567 | 0.78 | KMT2A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL2682787 | 0.78 | KMT2A (1.00) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL558024 | 0.78 | KMT2A (0.64) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL219769 | 0.78 | KMT2A (0.58) | RAB9AKMT2ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113307781-B | Synthesis method of 1,2, 3-thiadiazole derivative | 新疆大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-114573485-B | Method for synthesizing alkynyl alkyl sulfide | 华南理工大学 | 2023-11-10 | — | — | CN | disclosed |
| CN-114573485-A | Method for synthesizing alkynyl alkyl thioether | 华南理工大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112778067-B | Method for synthesizing thioamide compound by catalyzing 1,2, 3-thiadiazole compound and amine with copper | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-113307781-A | Synthetic method of 1,2,3-thiadiazole derivative | 新疆大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-112778067-A | Method for synthesizing thioamide compound by using copper to catalyze 1,2, 3-thiodiazole compound and amine | 华南理工大学 | 2021-05-11 | — | — | CN | disclosed |
| EP-1534700-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040072871-A1 | Novel thiophene derivatives, their process of preparation and the pharmaceutical compositions which comprise them | WARNER-LAMBERT COMPANY LLC | 2004-04-15 | — | — | US | disclosed |
| WO-2004018448-A1 | NOVEL THIOPHENE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
| EP-1394159-A1 | New thiophene derivatives, process for their preparation and pharmaceutical compositions containing them | Warner-Lambert Company LLC (US) | 2004-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072871-A1 | Novel thiophene derivatives, their process of preparation and the pharmaceutical compositions which comprise them | MMP11, MMP13, CBR1 | RAB9A 3435/4885KMT2A 4610/4885NPC1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.