Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615505 | 0.90 | ADRA2A (0.48) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL19705616 | 0.89 | ADRA2A (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL4407732 | 0.89 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL9700068 | 0.89 | ADRA2A (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL9700063 | 0.89 | ADRA2A (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL24931236 | 0.89 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL6250864 | 0.89 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL6250414 | 0.87 | CYP3A4 (0.49) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| Hydrochloric Acid SCHEMBL6248395 | 0.87 | CYP3A4 (0.49) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL10366921 | 0.85 | TSHR (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226377-A | Antibody drug conjugates comprising an eltrinastine derivative | 法马马有限公司 | 2021-08-06 | — | — | CN | disclosed |