Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19705616 | 1.00 | ADRA2A (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL9700068 | 1.00 | ADRA2A (0.47) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL28615504 | 0.89 | ADRA2A (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL31060300 | 0.87 | CYP1A2 (0.46) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL9094896 | 0.87 | CYP1A2 (0.46) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL28615505 | 0.87 | ADRA2A (0.48) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL29816355 | 0.86 | CYP2D6 (0.52) | LMNACYP1A2CYP2D6PKMSMN1; SMN2 | |
| SCHEMBL24931236 | 0.85 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL6250864 | 0.85 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL4407732 | 0.85 | CYP3A4 (0.50) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104490859-B | For treating dopy and improving the composition of dopy corelation behaviour | 爱思开生物制药株式会社 | 2017-09-22 | — | — | CN | claimed |
| CN-103025326-B | The method for the treatment of restless legs syndrome | SK BIOPHARMACEUTICALS CO.,LTD. (KR) | 2015-07-29 | — | — | CN | claimed |
| CN-104490859-A | Compositions For Treating Drug Addiction And Improving Addiction-related Behavior | SK BIOPHARMACEUTICALS CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-102695502-B | Compositions for treating drug addiction and improving drug addiction-related behavior | SK BIOPHARMACEUTICALS CO LTD | 2014-12-24 | — | — | CN | claimed |
| CN-102781436-B | Methods for treating fibromyalgia syndrome | SK BIOPHARMACEUTICALS CO LTD | 2014-01-08 | — | — | CN | claimed |
| CN-102762201-B | Methods for treating attention-deficit/hyperactivity disorder | SK BIOPHARMACEUTICALS CO LTD | 2013-12-18 | — | — | CN | claimed |
| CN-103025326-A | Methods of treating restless legs syndrome | SK BIOPHARMACEUTICALS CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102985085-A | Methods for treating bipolar disorder | SK BIOPHARMACEUTICALS CO LTD | 2013-03-20 | — | — | CN | claimed |
| CN-102781436-A | Methods for treating fibromyalgia syndrome | SK HOLDINGS CO LTD | 2012-11-14 | — | — | CN | claimed |
| CN-102762201-A | METHODS FOR TREATING ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | SK HOLDINGS CO LTD | 2012-10-31 | — | — | CN | claimed |
| CN-101217949-B | Treating Sleep-Wake Disorders | SK CORP | 2012-10-17 | — | — | CN | claimed |
| CN-102695502-A | Compositions for treating drug addiction and improving drug addiction-related behavior | SK HOLDINGS CO LTD | 2012-09-26 | — | — | CN | claimed |
| CN-101217949-A | Treating Sleep-Wake Disorders | SK CORP (KR) | 2008-07-09 | — | — | CN | claimed |
| CN-117479931-A | Methods for treating Autism Spectrum Disorder (ASD) | 爱思开生物制药株式会社 | 2024-01-30 | — | — | CN | disclosed |
| CN-110638805-A | Promoting cessation of smoking | 爵士制药国际III有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-110638804-A | Treating obesity | 爵士制药国际III有限公司 | 2020-01-03 | — | — | CN | disclosed |
| CN-102481274-A | Method for treating or preventing fatigue | SK BIOPHARMACEUTICALS CO LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-101217949-A | Treating Sleep-Wake Disorders | SK CORP (KR) | 2008-07-09 | — | — | CN | disclosed |
| CN-101132787-A | Adjunctive therapy for depression | SK CORP (KR) | 2008-02-27 | — | — | CN | disclosed |
| US-5079167-A | Enzymatic resolution of amino acid carbamate racemates | GESELLSCHAFT FUR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) (DE) | 1992-01-07 | — | — | US | disclosed |