Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18570683 | 0.85 | SCN8A (0.50) | ALDH1A1MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL4219396 | 0.82 | PTGDR2 (0.59) | ALDH1A1MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL4219060 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL1804090 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTHTTSMN1; SMN2KDM4E | |
| SCHEMBL29750441 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL21816541 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL11043316 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPTHTTSMN1; SMN2MEN1 | |
| SCHEMBL30873564 | 0.79 | PTPN1 (0.63) | — | |
| SCHEMBL29227186 | 0.79 | PTPN1 (0.63) | — | |
| SCHEMBL31005989 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113278022-B | Pyrazolopyrimidine compound, pharmaceutical composition and application thereof | 南京纳丁菲医药科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| CN-113278022-A | Pyrazolopyrimidine compounds, pharmaceutical compositions and uses thereof | 南京纳丁菲医药科技有限公司 | 2021-08-20 | — | — | CN | disclosed |