Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | PSEN1 | P49768 | 7/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PTGES | O14684 | 2/20 | 0.53 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | RXRG | P48443 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29227186 | 1.00 | PTPN1 (0.63) | PTPN1PSEN1ALOX5PPARGPTGES | |
| SCHEMBL5629722 | 0.92 | PTPN1 (0.54) | PTPN1PSEN1ALOX5PPARGPTGES | |
| SCHEMBL5631333 | 0.88 | MAOA (0.51) | PTPN1 | |
| SCHEMBL18002231 | 0.86 | PTPN1 (0.57) | PTPN1PSEN1ALOX5PPARGPTGES | |
| SCHEMBL30873532 | 0.85 | ALDH1A1 (0.48) | PTPN1PSEN1ALOX5PPARGPTGES | |
| SCHEMBL30679655 | 0.85 | PTPN1 (0.64) | PTPN1PSEN1ALOX5PPARGRXRA | |
| SCHEMBL29227159 | 0.85 | ALDH1A1 (0.48) | PTPN1PSEN1ALOX5PPARGPTGES | |
| SCHEMBL5699854 | 0.85 | PTPN1 (0.64) | PTPN1PSEN1ALOX5PPARGRXRA | |
| SCHEMBL29227151 | 0.83 | CCR5 (0.52) | PTPN1 | |
| SCHEMBL18002339 | 0.83 | MRGPRX4 (0.49) | PTPN1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946031-A | Substituted aromatic phenol derivatives of KNa1.1 channel inhibitors | 北京大学 | 2024-04-30 | — | — | CN | disclosed |