Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | IL4I1 | Q96RQ9 | 3/20 | 0.34 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 4/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23528801 | 0.84 | MEN1 (0.40) | IL4I1HSD17B13 | |
| SCHEMBL23528627 | 0.79 | MEN1 (0.41) | GRIN2BGRIN1 | |
| SCHEMBL29569822 | 0.79 | MEN1 (0.41) | GRIN2BGRIN1 | |
| SCHEMBL25438256 | 0.76 | MEN1 (0.35) | GRIN2BGRIN1 | |
| SCHEMBL23528573 | 0.73 | MEN1 (0.46) | — | |
| SCHEMBL29570039 | 0.71 | MET (0.40) | GRIN2BGRIN1 | |
| SCHEMBL23528516 | 0.71 | MET (0.40) | GRIN2BGRIN1 | |
| SCHEMBL29569687 | 0.69 | IL4I1 (0.43) | IL4I1HSD17B13ACHEBRD4HDAC6 | |
| SCHEMBL26531101 | 0.68 | MEN1 (0.44) | — | |
| SCHEMBL27068759 | 0.65 | MEN1 (0.42) | HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272291-A | Pyridazinone compound and use thereof | 艾知怀斯治疗学公司 | 2021-08-17 | — | — | CN | disclosed |