Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.33 |
| ▸ | GABRP | O00591 | 3/20 | 0.32 |
| ▸ | GABRD | O14764 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.32 |
| ▸ | GABRE | P78334 | 3/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.32 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.32 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.32 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615703 | 0.94 | TLR2 (0.33) | TLR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4738392 | 0.86 | PLA2G2C (0.36) | TLR2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28968784 | 0.85 | TLR2 (0.31) | TLR2CYP1A2LMNAKMT2A | |
| SCHEMBL28933423 | 0.82 | CYP3A4 (0.32) | THRB | |
| SCHEMBL3208469 | 0.82 | CYP3A4 (0.34) | CYP1A2LMNATHRBKMT2A | |
| SCHEMBL28968781 | 0.82 | TLR2 (0.31) | TLR2CYP1A2LMNAKMT2A | |
| SCHEMBL28553600 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL12997234 | 0.79 | CYP3A4 (0.32) | THRB | |
| SCHEMBL12997235 | 0.79 | CYP3A4 (0.32) | THRB | |
| SCHEMBL1984877 | 0.76 | CYP3A4 (0.40) | TLR2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113056287-A | Conjugated chemical degradation inducers and methods of use | 豪夫迈·罗氏有限公司 | 2021-06-29 | — | — | CN | disclosed |