SCHEMBL28968784

SCHEMBL28968784

CCOC(COCCN)OCC(=O)O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 2/20 0.31
CTH P32929 1/20 0.31
GLA P06280 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28968781 0.87 TLR2 (0.31) TLR2CTHGLAL3MBTL1MEN1
SCHEMBL28615705 0.85 TLR2 (0.33) TLR2CYP1A2KMT2ALMNA
SCHEMBL3208469 0.84 CYP3A4 (0.34) MEN1CYP1A2KMT2ALMNA
SCHEMBL28377447 0.83 ALDH1A1 (0.32) GLAL3MBTL1
SCHEMBL28615703 0.82 TLR2 (0.33) TLR2CYP1A2KMT2ALMNA
SCHEMBL21405225 0.80 GLA (0.37) CTHGLAL3MBTL1
SCHEMBL28933423 0.80 CYP3A4 (0.32)
SCHEMBL12997234 0.80 CYP3A4 (0.32)
SCHEMBL12997235 0.80 CYP3A4 (0.32)
SCHEMBL28553600 0.77 ALDH1A1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115968296-A C-type natriuretic peptides and methods of treating cancer therewith 药明公司 2023-04-14 CN claimed
CN-115803338-A C-type natriuretic peptide and method for treating acute lung injury 药明公司 2023-03-14 CN claimed
CN-115968296-A C-type natriuretic peptides and methods of treating cancer therewith 药明公司 2023-04-14 CN disclosed
CN-115803338-A C-type natriuretic peptide and method for treating acute lung injury 药明公司 2023-03-14 CN disclosed