Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL28906441 | 1.00 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC8TDP1CA12 | |
| SCHEMBL207817 | 0.97 | ALDH1A1 (0.58) | ALDH1A1TSHRHDAC8TDP1CA12 | |
| SCHEMBL2304245 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TSHRCA12CA2CA9 | |
| Phenylacetylene SCHEMBL11432458 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8TDP1 | |
| Phenylacetylene SCHEMBL28871467 | 0.81 | ALDH1A1 (0.64) | ALDH1A1TSHRHDAC8TDP1 | |
| Ethylene SCHEMBL7955374 | 0.78 | ALDH1A1 (0.92) | ALDH1A1TSHRHDAC8TDP1CHRNB2 | |
| SCHEMBL5892375 | 0.76 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL6005614 | 0.76 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL5892551 | 0.76 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 | |
| SCHEMBL6005617 | 0.76 | HDAC8 (0.43) | HDAC8CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920907-B | Aminated porous aromatic skeleton compound and preparation method and application thereof | 福建农林大学 | 2023-06-20 | — | — | CN | disclosed |
| CN-115572373-A | Organic porous polymer for organic dye adsorption and preparation method thereof | 山东大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-113321787-B | Nitroxide free radical functionalized porous organic polymer nanotube and preparation method and application thereof | 贵州师范大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-110183675-B | Hyperbranched polythioamide compound and preparation method and application thereof | 华南理工大学 | 2022-03-29 | — | — | CN | disclosed |
| CN-110218220-B | Functionalized metal-organic framework compound, complex formed by functionalized metal-organic framework compound, and preparation method and application of functionalized metal-organic framework compound | 中山大学 | 2021-11-12 | — | — | CN | disclosed |
| CN-113321787-A | Nitroxide free radical functionalized porous organic polymer nanotube and preparation method and application thereof | 贵州师范大学 | 2021-08-31 | — | — | CN | disclosed |