SCHEMBL2304245

SCHEMBL2304245

C#Cc1ccc(C#N)cc1.C=Cc1ccc(C#N)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
LMNA P02545 2/20 0.40
KDM4E B2RXH2 1/20 0.40
GAA P10253 1/20 0.40
FBP1 P09467 4/20 0.39
CYP2A6 P11509 2/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.36
MAOB P27338 2/20 0.36
HDAC2 Q92769 1/20 0.35
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127502 0.89 ALDH1A1 (0.58) ALDH1A1LMNAKDM4EGAAFBP1
SCHEMBL207817 0.89 ALDH1A1 (0.58) ALDH1A1CA12CA2CA9CA14
Ethylene SCHEMBL28615732 0.87 ALDH1A1 (0.55) ALDH1A1CA12CA2CA9CA14
Ethylene SCHEMBL28906441 0.87 ALDH1A1 (0.55) ALDH1A1CA12CA2CA9CA14
Benzaldehyde SCHEMBL2302571 0.85 ALDH1A1 (0.42) ALDH1A1LMNAKDM4EGAAFBP1
Benzene SCHEMBL28598325 0.85 ALDH1A1 (0.52) ALDH1A1LMNAKDM4EGAAFBP1
SCHEMBL10243387 0.83 MMP3 (0.52) ALDH1A1LMNAKDM4EGAAFBP1
SCHEMBL12567409 0.83 ALDH1A1 (0.50) ALDH1A1LMNAKDM4EGAAFBP1
SCHEMBL8351562 0.83 MMP3 (0.52) ALDH1A1LMNAKDM4EGAAFBP1
SCHEMBL853731 0.82 CA2 (0.52) ALDH1A1CYP2A6CA12CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092515-A1 FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY MICROMASS UK LIMITED (GB) 2011-08-04 WO disclosed