Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 4/20 | 0.55 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476100 | 1.00 | TLR2 (0.55) | TLR2MDM2PTPN1MMEECE1 | |
| SCHEMBL12476097 | 1.00 | TLR2 (0.55) | TLR2MDM2PTPN1MMEECE1 | |
| SCHEMBL18683448 | 1.00 | TLR2 (0.55) | TLR2MDM2PTPN1MMEECE1 | |
| SCHEMBL23253745 | 0.94 | TLR2 (0.52) | TLR2MDM2PTPN1MDM4TP53 | |
| SCHEMBL27041569 | 0.91 | TLR2 (0.49) | TLR2MDM2PTPN1MDM4TP53 | |
| SCHEMBL27041543 | 0.91 | TLR2 (0.49) | TLR2MDM2PTPN1MDM4TP53 | |
| SCHEMBL1000115 | 0.91 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL1044856 | 0.91 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL29398487 | 0.91 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL29382791 | 0.91 | TLR2 (0.62) | TLR2MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117310-B | Small molecule conjugates for intracellular delivery of biologically active compounds | 弗·哈夫曼-拉罗切有限公司 | 2021-04-06 | — | — | CN | disclosed |