SCHEMBL29398487

SCHEMBL29398487

CCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TLR2 O60603 4/20 0.62
MDM2 Q00987 6/20 0.59
MDM4 O15151 2/20 0.56
TP53 P04637 2/20 0.56
CASP3 P42574 1/20 0.53
TNF P01375 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29382791 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL1000115 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL30645689 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL1044856 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL29503829 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL7420121 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL29367120 1.00 TLR2 (0.62) TLR2MDM2MDM4TP53CASP3
SCHEMBL14996025 0.96 TLR2 (0.64) TLR2MDM2MDM4TP53CASP3
SCHEMBL14497949 0.96 TLR2 (0.64) TLR2MDM2MDM4TP53CASP3
SCHEMBL30802520 0.96 TLR2 (0.64) TLR2MDM2MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF NOVARTIS AG (CH) 2025-03-20 US disclosed
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2024-12-12 US disclosed
US-12097237-B2 Small molecule Ras inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2024-09-24 US disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
EP-4373835-A1 MACROCYLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2024-05-29 EP disclosed
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF CHENGDU SINTANOVO BIOTECHNOLOGY CO., LTD. (CN) 2024-05-16 US disclosed
CN-117940445-A Macrocyclic immunomodulators 百时美施贵宝公司 2024-04-26 CN disclosed
CN-114805487-B Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2024-03-12 CN disclosed
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES NOVARTIS AG (CH) 2024-02-29 US disclosed
EP-4321525-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF Chengdu Sintanovo Biotechnology Co., Ltd (CN) 2024-02-14 EP disclosed
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules NOVARTIS AG (CH) 2023-09-12 US disclosed
CN-113072617-B Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2023-08-08 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
WO-2023004240-A1 MACROCYLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-01-26 WO disclosed
WO-2022206587-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF 成都诺和晟泰生物科技有限公司 2022-10-06 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-114805487-A Polypeptide compound and application thereof 成都诺和晟泰生物科技有限公司 2022-07-29 CN disclosed
EP-3988170-A1 FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES Novartis AG (CH) 2022-04-27 EP disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
CN-114133443-A Fatty acids and their use in conjugation with biomolecules 诺华股份有限公司 2022-03-04 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12097237-B2 Small molecule Ras inhibitors KRAS, HRAS, NRAS TLR2 4770/4885MDM2 195/4885MDM4 904/4885
US-20240066132-A1 NOVEL FATTY ACIDS AND THEIR USE IN CONJUGATION TO BIOMOLECULES FABP1, FABP2, FABP3 TLR2 415/4885MDM2 2413/4885MDM4 4731/4885
US-11752211-B2 Fatty acids and their use in conjugation to biomolecules FABP1, FABP2, FABP3 TLR2 373/4885MDM2 2188/4885MDM4 4725/4885
US-20240158438-A1 POLYPEPTIDE COMPOUND AND APPLICATION THEREOF GHSR, GHRHR, GIPR TLR2 416/4885MDM2 4290/4885MDM4 4883/4885
US-20250090699-A1 FAP TARGETING CYCLIC PEPTIDES AND CONJUGATES THEREOF FAP, FIBP, FGF23 TLR2 3566/4885MDM2 1455/4885MDM4 2377/4885
US-20240409585-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 TLR2 123/4885MDM2 765/4885MDM4 1149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.