Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 9/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL155661 | 0.92 | TDP1 (0.61) | TDP1ERN1HDAC3HDAC4HDAC1 | |
| SCHEMBL14774601 | 0.79 | TDP1 (0.52) | TDP1ERN1HDAC3HDAC4HDAC1 | |
| SCHEMBL14774600 | 0.79 | TDP1 (0.52) | TDP1ERN1HDAC3HDAC4HDAC1 | |
| SCHEMBL42333 | 0.77 | ERN1 (0.59) | TDP1ERN1PTPN1KMT2ALMNA | |
| SCHEMBL29958016 | 0.77 | ERN1 (0.59) | TDP1ERN1PTPN1KMT2ALMNA | |
| SCHEMBL4552823 | 0.77 | TDP1 (0.48) | TDP1ERN1HSD17B10 | |
| SCHEMBL25078545 | 0.74 | TDP1 (0.55) | TDP1ERN1PTPN1HSD17B10 | |
| SCHEMBL21676102 | 0.73 | TDP1 (0.44) | TDP1ERN1HDAC3HDAC4HDAC1 | |
| SCHEMBL16599459 | 0.73 | TDP1 (0.44) | TDP1ERN1HDAC3HDAC4HDAC1 | |
| SCHEMBL28336792 | 0.73 | TDP1 (0.53) | TDP1ERN1PTPN1GRM2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113133969-B | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-113133969-A | Glucose-responsive insulin multivesicular liposome and preparation method and application thereof | 中国药科大学 | 2021-07-20 | — | — | CN | disclosed |