Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42333 | 1.00 | ERN1 (0.59) | ERN1TDP1HSD17B10PTPN1NFE2L2 | |
| SCHEMBL155661 | 0.84 | TDP1 (0.61) | ERN1TDP1HSD17B10PTPN1LMNA | |
| SCHEMBL4357334 | 0.80 | TDP1 (0.70) | ERN1TDP1HSD17B10PTPN1XDH | |
| SCHEMBL14774600 | 0.80 | TDP1 (0.52) | ERN1TDP1PTPN1NFE2L2MEN1 | |
| SCHEMBL14774601 | 0.80 | TDP1 (0.52) | ERN1TDP1PTPN1NFE2L2MEN1 | |
| SCHEMBL22039183 | 0.79 | ERN1 (0.42) | ERN1TDP1HSD17B10NFE2L2XDH | |
| SCHEMBL5175967 | 0.78 | SOS1 (0.44) | ERN1TDP1HSD17B10NFE2L2MEN1 | |
| SCHEMBL65723 | 0.78 | ERN1 (0.56) | ERN1PTPN1NFE2L2 | |
| Water SCHEMBL28578537 | 0.78 | TDP1 (0.67) | ERN1TDP1HSD17B10PTPN1XDH | |
| SCHEMBL42560 | 0.78 | TDP1 (0.67) | ERN1TDP1HSD17B10PTPN1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |