Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ME2 | P23368 | 1/20 | 0.41 |
| ▸ | ME1 | P48163 | 1/20 | 0.41 |
| ▸ | ME3 | Q16798 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694790 | 0.86 | MAPT (0.49) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| Hydrochloric Acid SCHEMBL31540771 | 0.81 | MAPT (0.57) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL899615 | 0.80 | MAPT (0.48) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL29742069 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL29742023 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2LMNAPOLBKDM4EHRH2 | |
| SCHEMBL30263282 | 0.79 | HRH3 (0.54) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL1459682 | 0.79 | MAPT (0.57) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL15569212 | 0.79 | MAPT (0.50) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL29742046 | 0.78 | MAPT (0.58) | SMN1; SMN2LMNAPOLBMAPTKDM4E | |
| SCHEMBL5358158 | 0.78 | MAPT (0.53) | SMN1; SMN2LMNAPOLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779117-B | Kinase inhibitor | 重庆复创医药研究有限公司 | 2021-08-31 | — | — | CN | disclosed |