Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | RNF4 | P78317 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615903 | 1.00 | KCNN4 (0.50) | KCNN4KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL22032531 | 0.85 | CYP1A2 (0.45) | KMT2AMAPTCYP1A2CYP3A4RECQL | |
| SCHEMBL22032530 | 0.85 | CYP1A2 (0.45) | KMT2AMAPTCYP1A2CYP3A4RECQL | |
| SCHEMBL7459501 | 0.83 | TP53BP1 (0.40) | KCNN4KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL1448419 | 0.80 | KCNN4 (0.56) | KCNN4KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL7452116 | 0.79 | PTPRC (0.45) | KMT2AMAPTMEN1CYP2C19ALDH1A1 | |
| SCHEMBL10635095 | 0.78 | HIF1A (0.44) | KCNN4KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL28625331 | 0.77 | KCNN4 (0.43) | KCNN4KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL28625328 | 0.77 | KCNN4 (0.43) | KCNN4KMT2AMAPTCYP1A2CYP3A4 | |
| SCHEMBL20608008 | 0.76 | KCNN4 (0.51) | KCNN4KMT2AMAPTSRCMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |