Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20608008 | 0.85 | KCNN4 (0.51) | KCNN4MAPTKMT2ASRCHDAC3 | |
| SCHEMBL8115153 | 0.83 | ALDH1A1 (0.58) | KCNN4MAPTKMT2AALDH1A1RECQL | |
| SCHEMBL21807366 | 0.83 | HDAC3 (0.46) | KCNN4MAPTELANEKMT2AALDH1A1 | |
| SCHEMBL28250865 | 0.83 | HDAC3 (0.46) | KCNN4MAPTELANEKMT2AALDH1A1 | |
| SCHEMBL30188924 | 0.81 | KCNN4 (0.51) | KCNN4MAPTELANEKMT2ASRC | |
| SCHEMBL28615904 | 0.80 | KCNN4 (0.50) | KCNN4MAPTKMT2ASRCALDH1A1 | |
| SCHEMBL28615903 | 0.80 | KCNN4 (0.50) | KCNN4MAPTKMT2ASRCALDH1A1 | |
| SCHEMBL23868362 | 0.80 | KCNN4 (0.58) | KCNN4MAPTELANEKMT2ASRC | |
| SCHEMBL21484936 | 0.80 | KCNN4 (0.58) | KCNN4MAPTELANEKMT2ASRC | |
| SCHEMBL11684190 | 0.80 | HDAC3 (0.43) | KCNN4MAPTELANEKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824421-A | Chiral phosphine-phosphoramidite ligand and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2021-05-21 | — | — | CN | disclosed |
| US-7910748-B2 | Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7902382-B2 | Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-20100133995-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-20100137553-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2010-06-03 | — | — | US | disclosed |
| US-7659410-B2 | Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2010-02-09 | — | — | US | disclosed |
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | FUJI XEROX CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070252519-A1 | Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium | ARL1, NOD1, NLRP1 | KCNN4 723/4885MAPT 1563/4885ELANE 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.