Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28625328 | 1.00 | KCNN4 (0.43) | KCNN4TLR8TLR7CYP1A2CYP3A4 | |
| SCHEMBL22032437 | 0.88 | CYP3A4 (0.40) | KCNN4TLR8TLR7CYP1A2CYP3A4 | |
| SCHEMBL22032438 | 0.88 | CYP3A4 (0.40) | KCNN4TLR8TLR7CYP1A2CYP3A4 | |
| SCHEMBL28615903 | 0.77 | KCNN4 (0.50) | KCNN4CYP1A2CYP3A4RECQLKMT2A | |
| SCHEMBL28615904 | 0.77 | KCNN4 (0.50) | KCNN4CYP1A2CYP3A4RECQLKMT2A | |
| SCHEMBL1448419 | 0.74 | KCNN4 (0.56) | KCNN4CYP1A2CYP3A4RECQLKMT2A | |
| SCHEMBL15362803 | 0.72 | CYP3A4 (0.50) | KCNN4TLR8TLR7CYP1A2CYP3A4 | |
| SCHEMBL29273279 | 0.71 | MAPT (0.46) | KCNN4TLR8TLR7KMT2AOPRM1 | |
| SCHEMBL20608008 | 0.70 | KCNN4 (0.51) | KCNN4KMT2AMEN1MAPTSRC | |
| SCHEMBL30188924 | 0.70 | KCNN4 (0.51) | KCNN4KMT2AMEN1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113365696-A | Pharmaceutical compounds and their use as inhibitors of ubiquitin-specific protease 19(USP19) | 阿尔麦克探索有限公司 | 2021-09-07 | — | — | CN | disclosed |