SCHEMBL28615947

SCHEMBL28615947

O=CNc1cccc(/N=N/c2cccc(NC=O)c2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPT P10636 3/20 0.36
NOS1 P29475 1/20 0.35
MEN1 O00255 2/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
THRB P10828 1/20 0.35
PLCG1 P19174 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A1 P04798 1/20 0.33
TSHR P16473 1/20 0.33
CYP1B1 Q16678 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LIMK1 P53667 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28257844 0.86 ALDH1A1 (0.50) ALDH1A1MAPTNOS1KMT2APOLB
SCHEMBL12129057 0.82 ALDH1A1 (0.67) ALDH1A1MAPTMEN1NPC1KMT2A
SCHEMBL13205331 0.81 CYP1A2 (0.35) ALDH1A1TSHRTDP1LIMK1
SCHEMBL11695263 0.75 ALDH1A1 (0.64) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL28214132 0.74 ALDH1A1 (0.56) ALDH1A1MEN1KMT2APOLBLIMK1
SCHEMBL4455128 0.74 ALDH1A1 (0.56) ALDH1A1MAPTMEN1NPC1KMT2A
SCHEMBL29960515 0.73 ALDH1A1 (0.53) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL4098064 0.73 ALDH1A1 (0.50) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL224028 0.73 ALDH1A1 (0.53) ALDH1A1MAPTMEN1NPC1RAB9A
SCHEMBL28766491 0.73 ALDH1A1 (0.54) ALDH1A1MAPTMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112604675-B Preparation method and application of azobenzene dicarboxamide bridged beta-cyclodextrin chiral stationary phase 南昌大学 2022-06-14 CN disclosed
CN-112604675-A Preparation method and application of azobenzene dicarboxamide bridged beta-cyclodextrin chiral stationary phase 南昌大学 2021-04-06 CN disclosed