SCHEMBL28616010

SCHEMBL28616010

CCC(C)c1cc(CCl)ccc1C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
RAB9A P51151 2/20 0.40
KDM4E B2RXH2 2/20 0.40
ACE2 Q9BYF1 2/20 0.38
PPARA Q07869 3/20 0.37
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
TSHR P16473 1/20 0.36
PPARG P37231 1/20 0.35
NPC1 O15118 1/20 0.35
KLKB1 P03952 1/20 0.34
CTSB P07858 1/20 0.34
MMP9 P14780 1/20 0.34
DNMT1 P26358 1/20 0.34
DNMT3B Q9UBC3 1/20 0.34
DNMT3L Q9UJW3 1/20 0.34
DNMT3A Q9Y6K1 1/20 0.34
RORC P51449 1/20 0.34
RARB P10826 3/20 0.34
KAT8 Q9H7Z6 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39297 0.79 CA12 (0.48) ALDH1A1RAB9AKDM4EACE2TSHR
SCHEMBL1356395 0.79 ACE2 (0.54) ALDH1A1RAB9AKDM4EACE2PPARA
SCHEMBL10821986 0.78 RORC (0.54) ALDH1A1RAB9AKDM4ETSHRPPARG
SCHEMBL27888029 0.78 ALDH1A1 (0.44) ALDH1A1RAB9AKDM4EACE2PPARA
SCHEMBL3201674 0.78 KDM4E (0.43) ALDH1A1RAB9AKDM4EACE2AKR1C2
SCHEMBL27904829 0.78 ALDH1A1 (0.44) ALDH1A1RAB9AKDM4EACE2PPARA
SCHEMBL1985350 0.75 AKR1C3 (0.47) ALDH1A1RAB9AKDM4EAKR1C2AKR1C1
SCHEMBL1712181 0.73 NR1H4 (0.50) ALDH1A1KDM4EPPARAKLKB1CTSB
Bromide SCHEMBL1596585 0.73 TSHR (0.57) ALDH1A1TSHRKLKB1CTSBMMP9
SCHEMBL21961149 0.73 TSHR (0.57) ALDH1A1KDM4EPPARATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372215-A Novel esterification method for synthesizing p-halomethyl benzoate 吉林大学 2021-09-10 CN disclosed