SCHEMBL2861613

SCHEMBL2861613

CCOC(=O)c1ccc(OCc2ccccc2)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.62
KMT2A Q03164 2/20 0.62
HSP90AA1 P07900 1/20 0.62
ALDH1A1 P00352 2/20 0.60
MAOB P27338 4/20 0.60
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
NMT1 P30419 4/20 0.55
NMT2 O60551 1/20 0.55
PPARG P37231 1/20 0.54
NR1H4 Q96RI1 1/20 0.53
LMNA P02545 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GABRA1 P14867 1/20 0.52
GABRG2 P18507 1/20 0.52
GABRB3 P28472 1/20 0.52
GABRA5 P31644 1/20 0.52
GABRA3 P34903 1/20 0.52
GABRA2 P47869 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5383428 0.91 KMT2A (0.63) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL11589577 0.86 MEN1 (0.65) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL22438915 0.86 MEN1 (0.65) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL4816779 0.85 MEN1 (0.63) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL5233589 0.85 MEN1 (0.63) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL10738550 0.84 MEN1 (0.62) MEN1KMT2AHSP90AA1ALDH1A1MAOB
SCHEMBL16269061 0.84 MAOB (0.67) MEN1KMT2AHSP90AA1MAOBNMT1
SCHEMBL28065631 0.84 ALDH1A1 (0.62) MEN1KMT2AALDH1A1MAOBNPC1
SCHEMBL9547750 0.83 MAOB (0.74) MEN1KMT2AALDH1A1MAOBNPC1
SCHEMBL1115026 0.83 MEN1 (0.67) MEN1KMT2AALDH1A1MAOBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1972676-B1 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH KK (JP) 2010-03-10 EP disclosed
US-7658979-B2 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20080231785-A1 LIQUID CRYSTAL ALIGNMENT FILM COMPOSITION, LIQUID CRYSTAL DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. (JP) 2008-09-25 US disclosed
EP-1972676-A1 Liquid crystal alignment film composition, liquid crystal device and display apparatus Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed