SCHEMBL28065631

SCHEMBL28065631

CCC(=O)c1ccc(OCc2ccccc2)cc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.62
RAB9A P51151 3/20 0.62
SMN1; SMN2 Q16637 3/20 0.62
NPC1 O15118 2/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
MAOB P27338 7/20 0.58
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
HTT P42858 1/20 0.52
MRGPRX4 Q96LA9 2/20 0.51
S1PR1 P21453 1/20 0.49
PRKX P51817 1/20 0.49
ACVR1 Q04771 1/20 0.49
S1PR5 Q9H228 1/20 0.49
MAOA P21397 3/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
NR4A2 P43354 2/20 0.48
NR4A1 P22736 1/20 0.48
NR4A3 Q92570 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11751536 0.86 MEN1 (0.62) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL9547750 0.86 MAOB (0.74) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL9748049 0.86 MAOB (0.74) ALDH1A1RAB9ASMN1; SMN2MAOBGAA
SCHEMBL28256912 0.86 MAOB (0.65) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL1115026 0.85 MEN1 (0.67) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL5063274 0.84 MEN1 (0.66) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
Hydrochloric Acid SCHEMBL9440728 0.84 MEN1 (0.66) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL2861613 0.84 MEN1 (0.62) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL9630397 0.83 MAOB (0.58) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1
SCHEMBL27731757 0.83 MAOB (0.58) ALDH1A1RAB9ASMN1; SMN2NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103796992-B Guanidinobenzoic acid compound ASTELLAS PHARMA INC. (JP) 2016-04-27 CN disclosed