Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 12/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ACR | P10323 | 1/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256906 | 0.87 | RAB9A (0.62) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28258456 | 0.87 | SNCA (0.61) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28256911 | 0.87 | MEN1 (0.56) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28256941 | 0.87 | KMT2A (0.61) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28256896 | 0.86 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28614249 | 0.85 | SNCA (0.64) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL20764249 | 0.84 | ACR (0.69) | MEN1KMT2AMAPTACRALPL | |
| SCHEMBL28626779 | 0.84 | MEN1 (0.54) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28617518 | 0.84 | MEN1 (0.59) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL28258627 | 0.84 | MEN1 (0.53) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108929271-A | Tyrosinase inhibitor and preparation method thereof and purposes | 中国药科大学 | 2018-12-04 | — | — | CN | claimed |
| CN-108929271-B | Tyrosinase inhibitor and preparation method and application thereof | 中国药科大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108929271-A | Tyrosinase inhibitor and preparation method thereof and purposes | 中国药科大学 | 2018-12-04 | — | — | CN | disclosed |