Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1700365 | 1.00 | TP53 (0.39) | TP53PRCPKCNH2SMN1; SMN2DPP4 | |
| SCHEMBL1700363 | 1.00 | TP53 (0.39) | TP53PRCPKCNH2SMN1; SMN2DPP4 | |
| SCHEMBL2944007 | 0.90 | TP53 (0.45) | TP53SMN1; SMN2L3MBTL3L3MBTL1LMNA | |
| SCHEMBL2944005 | 0.90 | TP53 (0.45) | TP53SMN1; SMN2L3MBTL3L3MBTL1LMNA | |
| SCHEMBL24107443 | 0.88 | CHRNB2 (0.42) | TP53SMN1; SMN2L3MBTL3L3MBTL1LMNA | |
| SCHEMBL25770092 | 0.88 | CHRNB2 (0.42) | TP53SMN1; SMN2L3MBTL3L3MBTL1LMNA | |
| SCHEMBL29284129 | 0.82 | TP53 (0.40) | TP53SMN1; SMN2DPP4DPP8DPP9 | |
| SCHEMBL16111972 | 0.79 | PRCP (0.41) | PRCPKCNH2SMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL31466475 | 0.76 | DPP4 (0.40) | PRCPKCNH2SMN1; SMN2DPP4L3MBTL3 | |
| SCHEMBL28929205 | 0.75 | L3MBTL3 (0.35) | PRCPKCNH2SMN1; SMN2L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897038-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维爱尔兰无限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-108175749-B | Melt-extruded solid dispersions containing apoptosis-inducing agents | 艾伯维爱尔兰无限公司 | 2021-09-10 | — | — | CN | disclosed |