⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL540879 | 0.81 | — | — | |
| Acetic Acid SCHEMBL30917333 | 0.76 | ALDH1A1 (0.74) | — | |
| SCHEMBL8908271 | 0.74 | — | — | |
| SCHEMBL10645462 | 0.74 | — | — | |
| SCHEMBL82451 | 0.74 | — | — | |
| SCHEMBL28956046 | 0.74 | — | — | |
| SCHEMBL1682671 | 0.74 | — | — | |
| SCHEMBL7584963 | 0.74 | — | — | |
| SCHEMBL28204577 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL4309576 | 0.73 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113329998-A | Sulfonimidyl amide compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113286784-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-113227055-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113166065-A | Compounds and compositions for treating conditions associated with NLRP activity | 诺华股份有限公司 | 2021-07-23 | — | — | CN | disclosed |