Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.37 |
| ▸ | HTR2B | P41595 | 8/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627234 | 0.88 | HTR1A (0.39) | HTR2CHTR2BHTR2AHTR1ASLC6A4 | |
| SCHEMBL28612754 | 0.82 | HTR2C (0.35) | HTR2CHTR2B | |
| SCHEMBL23856055 | 0.81 | HTR2C (0.33) | HTR2CHTR2BHTR2AHTR1ASLC6A4 | |
| SCHEMBL28629203 | 0.81 | HTR2C (0.37) | HTR2CHTR2BHTR2AHTR1ASLC6A4 | |
| SCHEMBL28631801 | 0.81 | HTR2C (0.37) | HTR2CHTR2BHTR2A | |
| SCHEMBL28617668 | 0.80 | HTR2C (0.34) | HTR2CHTR2B | |
| SCHEMBL24353419 | 0.79 | HTR2C (0.36) | HTR2CHTR2BHTR2ASLC6A4SLC6A2 | |
| SCHEMBL23748310 | 0.75 | HTR2C (0.34) | HTR2CHTR2B | |
| SCHEMBL23856048 | 0.73 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL23856051 | 0.73 | HTR2C (0.34) | HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195502-A | Macrocyclic influenza endonuclease inhibitors | 詹森生物制药有限公司 | 2021-07-30 | — | — | CN | disclosed |