Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 17/20 | 0.55 |
| ▸ | EP300 | Q09472 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28623973 | 0.83 | CREBBP (0.65) | CREBBPEP300 | |
| SCHEMBL28630407 | 0.77 | CREBBP (0.63) | CREBBPEP300KDM4EMEN1ALDH1A1 | |
| SCHEMBL14402986 | 0.73 | HCAR3 (0.72) | PKMALDH1A1MAPT | |
| SCHEMBL978546 | 0.73 | MAPT (0.64) | PKMKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL31331661 | 0.73 | MAPT (0.64) | PKMKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL17023558 | 0.73 | MAPT (0.58) | CREBBPPKMKDM4EMEN1ALDH1A1 | |
| SCHEMBL28617513 | 0.73 | KDM4E (0.68) | CREBBPEP300KDM4EALDH1A1 | |
| SCHEMBL1530164 | 0.71 | KDM4E (0.62) | PKMKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL11460094 | 0.70 | MAPK1 (0.56) | PKMKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL28613652 | 0.70 | CREBBP (0.68) | CREBBPEP300KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321640-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-09 | — | — | CN | disclosed |
| CN-109111427-B | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2023-06-02 | — | — | CN | disclosed |
| CN-113321640-A | Indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2021-08-31 | — | — | CN | disclosed |