SCHEMBL28616888

SCHEMBL28616888

O=P(O)(O)c1ccc(NP)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.54
CA4 P22748 1/20 0.54
CA5A P35218 1/20 0.54
LMNA P02545 2/20 0.34
TSHR P16473 1/20 0.34
CCNT1 O60563 2/20 0.34
CDK9 P50750 2/20 0.34
CA12 O43570 4/20 0.33
PGK1 P00558 3/20 0.33
PGK2 P07205 3/20 0.33
MMP2 P08253 3/20 0.33
CA1 P00915 2/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
CFTR P13569 1/20 0.33
MMP8 P22894 2/20 0.32
MMP9 P14780 1/20 0.32
MMP14 P50281 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171752 0.79 CA2 (0.71) CA2CA4CA5ALMNATSHR
SCHEMBL17362396 0.76 CA2 (0.54) CA2CA4CA5ALMNATSHR
SCHEMBL11163447 0.76 CA2 (0.54) CA2CA4CA5ALMNATSHR
SCHEMBL5059514 0.73 CA2 (0.70) CA2CA4CA5ATSHRCA12
SCHEMBL1828823 0.72 CA2 (0.55) CA2CA4CA5ALMNATSHR
SCHEMBL12313514 0.72 CA2 (0.55) CA2CA4CA5ALMNATSHR
SCHEMBL27471998 0.71 PEPD (0.57) CA2CA4CA5ALMNACA1
SCHEMBL8887300 0.71 SMN1; SMN2 (0.59) CA2CA4TSHRCA12CA1
SCHEMBL28488098 0.71 CA2 (0.48) CA2CA4CA5ACA12CA1
SCHEMBL22999982 0.71 CA2 (0.60) CA2CA4CA5ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087968-A Preparation method of phosphotailings based phenyl phosphonic acid pillared calcium magnesium aluminum hydrotalcite 武汉工程大学 2021-07-09 CN claimed